1Q1U, 4JQ0
2257
14167
ENSG00000114279
ENSMUSG00000022523
P61328
P61329
NM_004113NM_021032NM_001377292NM_001377293NM_001377294
NM_001276419NM_001276420NM_010199NM_183064NM_001357064
NP_004104NP_066360NP_001364221NP_001364222NP_001364223
NP_001263348NP_001263349NP_034329NP_898887NP_001343993
Fibroblast growth factor 12 is a protein that in humans is encoded by the FGF12 gene.[5][6][7]
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.[7]
This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.
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