D-ribulokinase

D-ribulokinase
Identifiers
EC no.2.7.1.47
CAS no.9026-40-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a D-ribulokinase (EC 2.7.1.47) is an enzyme that catalyzes the chemical reaction

ATP + D-ribulose ADP + D-ribulose 5-phosphate

Thus, the two substrates of this enzyme are ATP and D-ribulose, whereas its two products are ADP and D-ribulose 5-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-ribulose 5-phosphotransferase. This enzyme is also called D-ribulokinase (phosphorylating). This enzyme participates in pentose and glucuronate interconversions.

References

  • FROMM HJ (1959). "D-Ribulokinase from Aerobacter aerogenes". J. Biol. Chem. 234 (12): 3097–101. doi:10.1016/S0021-9258(18)69628-0. PMID 13825363.
  • Singh C, Glaab E, Linster C (2016). "Molecular Identification of D-Ribulokinase in Budding Yeast and Mammals". J. Biol. Chem. 292 (3): 1005–1028. doi:10.1074/jbc.M116.760744. PMC 5247636. PMID 27909055.


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