From 2008 to 2017, Cécile Debray was chief curator in charge of modern collections at the National Museum of Modern Art-Centre Pompidou.
In 2009 she was co-curator with Camille Morineau of Elles@centrepompidou a female artists' exhibition, for which she was in charge of the travelling exhibition through the United States and Brazil with a selection of artworks focused on the American and Brazilian scenes.[8]
A specialist in Henri Matisse, in 2012, she revealed the conceptual dimension of Matisse's work through the exhibition Matisse, Pairs and series highlighting the repetitive exploration of the same subject, of the same motif, which allowed the artist to explore painting.
In 2015, she designed the Marcel Duchamp monographic exhibition La peinture même. Cécile Debray shows the painting and the drawings which led the artist to the realization of the Grand Verre, La mariée mise à nu par ses célibataires, même, from 1910 to 1923. A new approach, the exhibition intends to show the paintings of the one who, according to the modernist doxa, wanted to kill painting.
In 2017, she succeeded Laurence des Cars as director of the Musée de l'Orangerie. She rethinks the presentation of the collections which has been accompanied by a renovation and redesign of spaces, and sets up "Contemporary Counterpoints", with artists such as Otobong Nkanga, Richard Jackson and Ann Veronica Janssens.
Cécile Debray is promoting in France in 2020 the work of the Portuguese artist Paula Rego, the only woman in the School of London, a figure of the movement against violence towards women and the ambivalence of childhood, which she exhibits at the museum of the Orangery. Invited by Jean de Loisy to the programme "L'art est la matière" (Art is matter) on France Culture, she says:
The Orangery is a setting that allows a unique enhancement of the works. Thus, Paula Rego's pastels unfold in all their sensuality, between a very raw realism and a Hispanic baroque.
In 2021, Cécile Debray is continuing her programme of historical exhibitions at the Musée de l'Orangerie with Soutine / de Kooning: La peinture incarnee (The Incarnate Painting), from September 14, 2021, to January 10, 2022, and David Hockney: The four seasons, from October 12, 2021, to February 10, 2022.[9]
Exhibition curator (selection)
As exhibition curator, Cécile Debray has designed and organized around twenty major exhibitions in unexplored territories, including Elles@centrepompidou in 2009 at the Center Pompidou, Dada Africa. Sources et influences extra-occidentales (Dada Africa. Extra-Western sources and influences) in 2017 at the Musée de l'Orangerie or Le modèle noir de Géricault à Matisse (The Black model from Géricault to Matisse in 2019 at the Musée d'Orsay.
Le Nouveau Réalisme (New Realism), Grand Palais, March - July 2007