In enzymology, a CDP-ribitol ribitolphosphotransferase (EC 2.7.8.14) is an enzyme that catalyzes the chemical reaction

CDP-ribitol + (ribitol phosphate)n ${\displaystyle \rightleftharpoons }$ CMP + (ribitol phosphate)n⁺1

Thus, the two substrates of this enzyme are CDP-ribitol and (ribitol phosphate)n, whereas its two products are CMP and (ribitol phosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase. Other names in common use include teichoic-acid synthase, polyribitol phosphate synthetase, teichoate synthetase, poly(ribitol phosphate) synthetase, polyribitol phosphate polymerase, and teichoate synthase.

• Ishimoto N, Strominger JL (1966). "Polyribitol phosphate synthetase of Staphylococcus aureus". J. Biol. Chem. 241 (3): 639–50. PMID 5908130.