In 2021, Clarke was elected as the London Assembly Member for Barney and Camden, being subsequently elected in 2024. She won 70,749 votes, 19,143 more than Julie Redmond, the Conservative Party Candidate, who came second.[5]
Clarke is the Labour group spokesperson for Fire at the London Assembly, having lobbied for Londoners still living in homes with unsafe cladding and advocating for all recommendations from the Grenfell Tower Inquiry implemented.
She has also fought for firefighters' pay and conditions to ensure the London Fire Brigade has enough staff, advocating for staff throughout the Brigade's Culture Review and "engage" process, colloquially known as being in "special measures", which started in 2022 and concluded in 2024.[6]
Clarke has campaigned for better regulation of lithium-ion batteries,[7] obtaining data showing that they cause a fire every two days in London.
Anne also chaired the Assembly's Fire, Resilience and Emergency Planning Committee throughout 2022/23 and 2023/24.[8]
Currently, she serves as a member on the London Assembly Budget and Performance Committee, as well as the Economy, Culture and Skills Committee and the Fire Committee.[8]
She is a volunteer at Childs Hill foodbank in her constituency.