Amairani was born in Mexico City, Mexico on 6 April 1970. She is the daughter of actress Anabel Gutiérrez. Amairani debuted as an actress in the 1988 telenovela Dulce desafío. She later appeared in the 1989 telenovela Simplemente Maria as Laura Rivera del Villar, followed by playing an antagonist in the 1992 telenovela Mágica juventud.
She also appeared in the telenovela Más allá del puente as Lupita, replacing Itati Cantoral from the prequel De frente al sol. In 1994, she again played the role of an antagonist in Marimar. Before her retirement, her last acting role was in La sombra del otro. In 1996, she decided to retire from telenovelas, at least for the time being, to be a mother for her three children. After her last childbirth, she had complications, including paralysis, weight gain and severe depression.