Abdu'l-Aziz Khan may refer to:

• Abdu'l-Aziz (1614–1683), ruler of the Khanate of Bukhara (1645–1680)
• Abdulaziz (1830–1876), Ottoman sultan
• Abdul Aziz Khan (cricketer) (fl. 1912–1926)
• Abdul Aziz Khan (Mughal governor), Mughal governor of Shivner; see Shivaji's Southern Campaign
• Abdul Aziz Khan Kaka, Pashtun Nationalist representing freedom fighters against the British Raj

This disambiguation page lists articles associated with the title Abdu'l-Aziz Khan.
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