The 2023 Open de Vendée was a professional tennis tournament played on hard courts. It was the 10th edition of the tournament which was part of the 2023 ATP Challenger Tour. It took place in Mouilleron-le-Captif, France between 2 and 8 October 2023.
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
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