Internacional started the season under coach 'Cacique' Medina, but soon found itself in a bad situation after a sub-par performance in the Campeonato Gaúcho, being knocked out by rivals Gremio thanks to a 3–0 home defeat in the knockout round which the team was unable to turn around even after winning at the Arena do Grêmio in the 2nd leg.
Moreover, Inter managed to suffer one of the worst defeats of its history after being knocked out in the First Round of the Copa do Brasil to a 2–0 defeat to minnows Globo FC, pilling pressure on the team and Medina. The Uruguayan was sacked after a 1–1 draw at Beira-Rio vs Guaireña, prompting the hiring of veteran and Rio Grande do Sul-born Mano Menezes.
Under Menezes, the Colorado slowly managed to find consistency, also greatly after the signings of players like Wanderson, Carlos De Pena, Vitão, Renê, Gabriel, Pedro Henrique and Alan Patrick. Inter qualified to the Sudamericana quarterfinals, a campaign highlighted by a comeback vs Colo Colo with a big 4–1 win at Beira-Rio, but was eliminated on its home soil to Melgar on penalties.
Internacional soon piled good results in the Brasileirão and was constantly on the races for the top spot, but was unable to reach eventual champions Palmeiras and found themselves Serie A runner-ups once again, the fifth time it happened in the 21st century.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Updated to match(es) played on unknown. Source: Soccerway Rules for classification: 1) Points; 2) Wins; 3) Goal difference; 4) Goals scored; 5) fewest red cards; 6) fewest yellow cards; 7) Draw in the headquarters of the FGF.
Note: The match was originally supposed to take place on 26 February at 19:00, but was postponed due to the fact that the Grêmio bus was stoned by Internacional fans.
Source: CBF Rules for classification: 1) points; 2) wins; 3) goal difference; 4) goals scored; 5) head-to-head results (only between two teams); 6) fewest red cards; 7) fewest yellow cards; 8) drawing of lots. (C) Champions Notes:
^Flamengo qualified for the Copa Libertadores group stage by winning the 2022 Copa Libertadores. Since they also won the 2022 Copa do Brasil, the berth awarded to the Copa do Brasil champions (Copa Libertadores group stage) was passed over to the league's best placed team not already qualified.
