The women's 5000 meter at the 2022 KNSB Dutch Single Distance Championships in Heerenveen took place at Thialf ice skating rink on Sunday 31 October 2021. Although the tournament was held in 2021 it was the 2022 edition as it was part of the 2021–2022 speed skating season. There were 12 participants. The first 5 skaters were eligible for the following World Cup tournaments