The inaugural edition was originally scheduled for September 6, 2020, but it was postponed to 2021 due to the COVID-19 pandemic.[2] With the Tour of California, the only American UCI World Tour event, on indefinite hiatus, and the Tour of Utah, the only other American UCI ProSeries race, remaining cancelled due to the COVID-19 pandemic, the Maryland Cycling Classic would have been the highest level road cycling race in the United States in 2021.[3]
However, on July 2, 2021, race organizers decided to postpone the race again, with the inaugural edition now expected to take place in 2022.[4]
As of the announcement of the cancellation of the race, two UCI WorldTeams, one UCI ProTeam, and seven UCI Continental teams made up the ten teams that would have participated in the race, with race organizers originally expecting to invite six to eight more teams.[7]