The 2021 Bredene Koksijde Classic was the 18th edition of the Bredene Koksijde Classic road cycling one day race, which was held on 19 March 2021, starting and finishing in the titular towns of Bredene and Koksijde, respectively.[2] The 1.Pro-category race was initially scheduled to be a part of the inaugural edition of the UCI ProSeries, but after the 2020 edition was cancelled due to the COVID-19 pandemic, it made its UCI ProSeries debut in 2021, while also still being a part of the 2021 UCI Europe Tour.[3]