2021 Internationaux de Tennis de Vendée
Date	4–10 October
Edition	8th
Surface	Hard (Indoor)
Location	Mouilleron-le-Captif, France
Champions
Singles
Jiří Veselý
Doubles
Jonathan Eysseric / Quentin Halys
← 2019 · Internationaux de Tennis de Vendée · 2022 →

The 2021 Internationaux de Tennis de Vendée was a professional tennis tournament played on hard courts. It was the eighth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Mouilleron-le-Captif, France between 4 and 10 October 2021.

Country	Player	Rank1	Seed
FRA	Benjamin Bonzi	64	1
CZE	Jiří Veselý	86	2
GER	Peter Gojowczyk	87	3
ITA	Andreas Seppi	95	4
FRA	Gilles Simon	99	5
FRA	Pierre-Hugues Herbert	100	6
LTU	Ričardas Berankis	106	7
SVK	Norbert Gombos	114	8

• ¹ Rankings are as of 27 September 2021.^[1]

The following players received wildcards into the singles main draw:

• Arthur Fils
• Kyrian Jacquet
• Harold Mayot

The following player received entry into the singles main draw as an alternate:

• Constant Lestienne

The following players received entry from the qualifying draw:

• Zizou Bergs
• Titouan Droguet
• Evgeny Karlovskiy
• Mats Rosenkranz

The following player received entry as a lucky loser:

• Kenny de Schepper

• Jiří Veselý def. Norbert Gombos 6–4, 6–4.

• Jonathan Eysseric / Quentin Halys def. David Pel / Aisam-ul-Haq Qureshi 4–6, 7–6^(7–5), [10–8].