The 2016–17 season of the NOFV-Oberliga Nord saw four new clubs in the league. VSG Altglienicke, SV Grün-Weiß Brieselang and FC Mecklenburg Schwerin were all promoted from the Verbandsligas while FSV Optik Rathenow was relegated from the Regionalliga Nordost.
The 2016–17 season of the NOFV-Oberliga Süd saw four new clubs in the league. BSG Chemie Leipzig and SV Merseburg 99 were promoted from the Landesligas or Verbandsligas while VfB Germania Halberstadt was relegated from the Regionalliga Nordost and Brandenburger SC Süd 05 moved from the northern division.