Singles
2016 San Luis Open Challenger Tour
Final
Champions	Peđa Krstin
Runners-up	Marcelo Arévalo
Score	6–4, 6–2
Events
Singles Doubles
← 2015 · San Luis Open Challenger Tour · 2017 →

Guido Pella was the defending champion, but chose not to defend his title.

Peđa Krstin won the title, defeating Marcelo Arévalo 6–4, 6–2 in the final.

	Semifinals							Final
		Federico Gaio	1	4
	Q	Marcelo Arévalo	6	6
								Q	Marcelo Arévalo	4	2
									Peđa Krstin	6	6
		Peđa Krstin	6	6
	2	Albert Montañés	2	4

	First round							Second round							Quarterfinals							Semifinals
	1	M Berrer	3	77	5
		F Gaio	6	65	7				F Gaio	6	6
		N Milojević	6	6					N Milojević	3	1
		O Roca Batalla	4	3												F Gaio	6	6
	WC	M Sánchez	3	2											7	H Podlipnik	4	1
		J Samper Montaña	6	6					J Samper Montaña	3	4
		J Jung	4	0				7	H Podlipnik	6	6
	7	H Podlipnik	6	6																			F Gaio	1	4
	3	A Ghem	7	77																		Q	M Arévalo	6	6
		D Novak	5	62				3	A Ghem	6	6
	WC	L Gómez	6	6				WC	L Gómez	3	2
		D Popko	2	0											3	A Ghem	3	65
	Q	M Arévalo	6	6											Q	M Arévalo	6	77
	WC	Mauricio Astorga	2	3				Q	M Arévalo	61	6	6
		D Nguyen	4	4				5	M Donati	77	4	3
	5	M Donati	6	6

	First round							Second round							Quarterfinals							Semifinals
	6	M Bourgue	5	6	6
	Alt	N Barrientos	7	2	0			6	M Bourgue	3	4
		P Krstin	6	6					P Krstin	6	6
	WC	T Hank	3	4												P Krstin	77	6
	Q	Robin Staněk	6	6											Q	C Zampieri	64	3
		R Ramírez Hidalgo	3	4				Q	R Staněk	3	1
	Q	C Zampieri	6	1	7			Q	C Zampieri	6	6
	4	A Menéndez Maceiras	1	6	5																		P Krstin	6	6
	8	J McGee	4	2																		2	A Montañés	2	4
		M Safwat	6	6					M Safwat	79	6
		G Lapentti	4	3					L Giustino	67	4
		L Giustino	6	6												M Safwat	6	2	65
	Q	A Velotti	5	6	0										2	A Montañés	4	6	77
		L Djere	7	3	6				L Djere	5	65
		P Cachin	7	3	65			2	A Montañés	7	77
	2	A Montañés	5	6	77

• Main draw
• Qualifying draw