Roger Federer defeated Andy Murray in the final, 6–3, 6–4, 7–6(13–11) to win the men's singles tennis title at the 2010 Australian Open.[1][2] It was his fourth Australian Open title and 16th major title overall. For the last time in his career, Federer became the reigning champion at three of the four majors, having also won the previous year's French Open and Wimbledon Championships, and missing out only on the US Open (where he finished runner-up to Juan Martín del Potro).
Rafael Nadal was the defending champion, but retired due to a right knee injury in the quarterfinals against Murray.[3] It would be Nadal's only loss at the majors this year, as he would go on to sweep the French Open, Wimbledon Championships, and the US Open.
This event marked the last major appearance for former world No. 1, 1997 finalist and 1998 French Open champion Carlos Moyá.