The 2005 Bucknell Bison football team was an American football team that represented Bucknell University during the 2005 NCAA Division I-AA football season. It finished last in the Patriot League.

Bucknell played its home games at Christy Mathewson–Memorial Stadium on the university campus in Lewisburg, Pennsylvania.

In its third year under head coach Tim Landis, the Bison compiled a 1–10 record.^[1] Sean Conover and Stephen Watts were the team captains.^[2]

The Bison were outscored 332 to 179. Bucknell's winless (0–6) conference record finished seventh in the Patriot League standings.^[3]

Date	Opponent	Site	Result	Attendance	Source
September 3	Georgetown	Christy Mathewson–Memorial Stadium Lewisburg, PA	L 16–19 OT	6,802	[4]
September 10	at Stony Brook*	Kenneth P. LaValle Stadium Stony Brook, NY	L 18–21	4,101	[5]
September 17	at Cornell*	Schoellkopf Field Ithaca, NY	L 7–24	12,723	[6]
October 1	Marist*	Christy Mathewson–Memorial Stadium Lewisburg, PA	W 27–7	6,250	[7]
October 8	at Penn*	Franklin Field Philadelphia, PA	L 7–53	5,245	[8]
October 15	Villanova*	Christy Mathewson–Memorial Stadium Lewisburg, PA	L 10–38	3,259	[9]
October 22	No. 21 Lehigh^	Christy Mathewson–Memorial Stadium Lewisburg, PA	L 10–42	2,695	[10]
October 29	at Lafayette	Fisher Field Easton, PA	L 20–33		[1]
November 5	at Fordham	Coffey Field Bronx, NY	L 21–28	3,766	[11]
November 12	at Colgate	Andy Kerr Stadium Hamilton, NY	L 10–16		[1]
November 19	Holy Cross	Christy Mathewson–Memorial Stadium Lewisburg, PA	L 33–51	3,120	[12]
*Non-conference game Homecoming ^ Parents Weekend Rankings from The Sports Network Poll released prior to the game