The 1980 Bucknell Bison football team was an American football team that represented Bucknell University as an independent during the 1980 NCAA Division I-AA football season.

In their sixth year under head coach Bob Curtis, the Bison compiled a 6–4 record.^[1] Joe Catalano, Dave Hibbard and Bruce Keltie were the team captains.^[2]

Bucknell played its home games at Memorial Stadium on the university campus in Lewisburg, Pennsylvania.

Date	Opponent	Site	Result	Attendance	Source
September 13	at Connecticut	Memorial Stadium Storrs, CT	L 7–38	7,670	[3]
September 20	Slippery Rock	Memorial Stadium Lewisburg, PA	W 25–6		[1]
September 27	at Brown	Brown Stadium Providence, RI	W 28–20	7,000	[4]
October 4	at Davidson	Richardson Stadium Davidson, NC	L 13–21	4,300	[5]
October 11	Lafayette	Memorial Stadium Lewisburg, PA	W 14–0		[1]
October 18	West Chester^	Memorial Stadium Lewisburg, PA	W 31–21		[1]
October 25	at No. 3 Lehigh	Taylor Stadium Bethlehem, PA	L 0–13	5,000	[6]
November 1	Cornell	Memorial Stadium Lewisburg, PA	W 33–16	2,500	[7]
November 8	Colgate	Memorial Stadium Lewisburg, PA	L 14–17	2,500	[8]
November 15	at No. 4 Boston University	Nickerson Field Boston, MA	W 30–17	2,200	[9]
Homecoming ^ Parents Weekend Rankings from Associated Press Poll released prior to the game