2-Formylbenzoate dehydrogenase

2-Formylbenzoate dehydrogenase
Identifiers
EC no.1.2.1.78
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

2-Formylbenzoate dehydrogenase (EC 1.2.1.78, 2-carboxybenzaldehyde dehydrogenase, 2CBAL dehydrogenase, PhdK) is an enzyme with systematic name 2-formylbenzoate:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

2-formylbenzoate + NAD+ + H2O o-phthalic acid + NADH + H+

The enzyme is involved in phenanthrene degradation.

References

  1. ^ Iwabuchi T, Harayama S (October 1997). "Biochemical and genetic characterization of 2-carboxybenzaldehyde dehydrogenase, an enzyme involved in phenanthrene degradation by Nocardioides sp. strain KP7". Journal of Bacteriology. 179 (20): 6488–94. PMC 179567. PMID 9335300.
  2. ^ Kiyohara H, Nagao K, Yano K (1981). "Isolation and some properties of NAD-linked 2-carboxybenzaldehyde dehydrogenase in Alcaligenes faecalis AFK 2 grown on phenanthrene". J. Gen. Appl. Microbiol. 27: 443–455. doi:10.2323/jgam.27.443.

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