In enzymology, a 2,3-diaminopropionate N-oxalyltransferase (EC 2.3.1.58) is an enzyme that catalyzes the chemical reaction

oxalyl-CoA + L-2,3-diaminopropanoate ${\displaystyle \rightleftharpoons }$ CoA + N₃-oxalyl-L-2,3-diaminopropanoate

Thus, the two substrates of this enzyme are oxalyl-CoA and L-2,3-diaminopropanoate, whereas its two products are CoA and N3-oxalyl-L-2,3-diaminopropanoate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase. Other names in common use include oxalyldiaminopropionate synthase, ODAP synthase, oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase, oxalyldiaminopropionic synthase, and oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase.

• Malathi K, Padmanaban G, Sarma PS (1970). "Biosynthesis of beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, the Lathyrus sativus neurotoxin". Phytochemistry. 9 (7): 1603–1610. doi:10.1016/S0031-9422(00)85283-8.