Date | Opponent | Rank | Site | TV | Result |
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September 5 | Midwestern State* | No. 9 | | | W 55–16 |
September 12 | Wayne State (NE)* | No. 9 | - Bearcat Stadium
- Maryville, MO
| | W 51–2 |
September 17 | at Missouri Southern | No. 9 | | | W 48–21 |
September 26 | Missouri Western | No. 6 | - Bearcat Stadium
- Maryville, MO (rivalry)
| | W 45–32 |
October 3 | at Washburn | No. 4 | | | W 38–31 |
October 10 | Missouri–Rolla | No. 4 | - Bearcat Stadium
- Maryville, MO
| | W 49–6 |
October 17 | at Southwest Baptist | No. 3 | | | W 57–12 |
October 24 | Pittsburg State | No. 4 | - Bearcat Stadium
- Maryville, MO (rivalry)
| | W 23–18 |
October 31 | at Central Missouri State | No. 2 | | | W 34–20 |
November 7 | at Truman State | No. 2 | | | W 41–7 |
November 14 | No. 10 Emporia State | No. 2 | - Bearcat Stadium
- Maryville, MO
| | W 69–33 |
November 21 | No. 16 Nebraska–Omaha* | No. 2 | | | W 28–14 |
November 28 | No. 6 Northern Colorado* | No. 2 | - Bearcat Stadium
- Maryville, MO (Division II Quarterfinal)
| | W 42–17 |
December 5 | No. 11 Texas A&M–Kingsville* | No. 2 | - Bearcat Stadium
- Maryville, MO (NCAA Division II Semifinal)
| | W 49–34 |
December 12 | No. 3 Carson–Newman* | No. 2 | | ESPN2 | W 24–6 |
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