The Lions football program began in 1968. Their first head coach was Jim Johnson. Under coach Jim Frazier the Lions won the 1972 NAIA Division II football championship.[2]
Conferences
From its inaugural season in 1968 until 1975, Missouri Southern played as an independent program. In 1976, it joined the Central States Intercollegiate Conference in which the school won one conference championships before leaving to play as an NCAA Division II member of the Missouri Intercollegiate Athletic Association (later renamed Mid-America Intercollegiate Athletics Association) in 1989, where the Lions have since remained a member and have won one conference championship.