The 1991–92 IHF Women's Cup Winners' Cup was the 16th edition of IHF's competition for European women's handball national cup champions. Contested by 23 teams, it ran from September 29, 1991, to April 20, 1992.

Defending champion Radnički Belgrade again won the competition, beating Debreceni VSC in a rematch of the previous season's semifinals. It was Radnički's third Cup Winners' Cup and the last of their six European trophies.^[1] This was the last edition where the Soviet Union was represented as it was dissolved one month after Spartak Kyiv was knocked out in the Round of 16, while Croatia made its debut as an independent country.

This list is incomplete; you can help by adding missing items. (October 2013)

	Preliminary round September 29 – October 5, 1991						Round of 16 November 10–17, 1991						Quarterfinals January 11–19, 1992						Semifinals February 5–23, 1992						Final April 5–20, 1992
	Podravka Koprivnica	30	40	70
	Cyprus College	19	16	35			Podravka Koprivnica	31	26	57
	Fémina Visé			?			Fémina Visé	19	8	27
	HC Berchem			?									Podravka Koprivnica	24	17	41
													Debreceni VSC	17	32	49
							Debreceni VSC	38	33	71
	Halfbank Ankara			?			Halbank Ankara	15	21	36
	NSA Sofia			?															Debreceni VSC (a)	19	23	42
																			Byåsen IL	19	23	42
							Byåsen IL	23	25	48
							WAT Fünfhaus	17	23	40
													Byåsen IL (a)	11	22	33
	VeL Geleen	17	14	31									ASPTT Metz	16	17	33
	ASPTT Metz	23	21	44			ASPTT Metz			?
	Västerås Irsta	26	28	54			Västerås Irsta			?
	Pogoń Szczecin	20	23	43																					Debreceni VSC	26	19	45
																									Radnički Belgrade (a)	21	24	45
							Ştiinţa Bacău	32	29	61
							Spartak Kyiv	19	25	44
													Ştiinţa Bacău	26	18	44
													Radnički Belgrade	21	25	46
							Ikast FS	21	18	39
							Radnički Belgrade	30	28	58
																			Radnički Belgrade	21	21	42
																			Bayer Leverkusen	18	22	40
							Bayer Leverkusen	24	25	49
							Slovan Duslo Šaľa	17	20	37
													Bayer Leverkusen	41	31	72
	Kiryat Sharet Holon	15	7	22									HC Sassari	17	19	36
	HC Sassari	28	38	66			HC Sassari			?
	EMT Pegaso	16		?			CD Paços de Arcos			?
	CD Paços de Arcos	14		?