The 1975 U.S. Pro Indoor – Singles was an event of the 1975 U.S. Pro Indoor tennis tournament and was played on outdoor carpet courts at the Spectrum in Philadelphia, Pennsylvania in the United States from January 20 through January 26, 1975. The draw comprised 82 players and 16 of them were seeded. Second-seeded Rod Laver was the defending U.S. Pro Indoor singles champion but lost in the second round in this edition. Seventh-seeded Marty Riessen won the title by defeating unseeded Vitas Gerulaitis in the final, 7–6(7–1), 5–7, 6–2, 6–7(0–7), 6–3.