The 1972-73 KNVB Cup was the 55th edition of the Dutch national football annual knockout tournament for the KNVB Cup. 46 teams contested, beginning on 29 October 1972 and ending at the final on 31 May 1973.

Ajax unsuccessfully defended its 1972 title losing on 10 December 1972 in the Second round, when the 18 Eredivisie teams entered this round, NAC, 2–2 (penalty shootout).

NAC successfully pursued its first KNVB Cup defeating NEC, 2–0. NAC contested in the Cup Winners' Cup.

• All 18 participants of the Eredivisie 1972-73, entering in the second round
• All 20 participants of the Eerste Divisie 1972-73
• 8 teams from lower (amateur) leagues

₁ Eerste Divisie; _A Amateur teams

The 18 Eredivisie teams entered this round.

_E Eredivisie

31 May 1973

NAC	2–0	NEC
Bish 10' Brouwers 75'

De Kuip, Rotterdam

Attendance: 45,801

Referee: Theo Boosten

NAC would participate in the Cup Winners' Cup.

• Eredivisie 1972-73
• Eerste Divisie 1972-73

• Netherlands Cup Full Results 1970–1994