In enzymology, a 1,2-dihydrovomilenine reductase (EC 1.3.1.73) is an enzyme that catalyzes the chemical reaction

17-O-acetylnorajmaline + NADP⁺ ${\displaystyle \rightleftharpoons }$ 1,2-dihydrovomilenine + NADPH + H⁺

Thus, the two substrates of this enzyme are 17-O-acetylnorajmaline and NADP⁺, whereas its 3 products are 1,2-dihydrovomilenine, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 17-O-acetylnorajmaline:NADP+ oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

• Gao S, von Schumann G, Stockigt J (2002). "A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline". Planta Medica. 68 (10): 906–11. doi:10.1055/s-2002-34935. PMID 12391554.