Chinonin
| Strukturformel | |||||||||||||||||||
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| Allgemeines | |||||||||||||||||||
| Name | Chinonin | ||||||||||||||||||
| Andere Namen | |||||||||||||||||||
| Summenformel | C19H18O11 | ||||||||||||||||||
| Kurzbeschreibung |
gelblicher Feststoff[2] | ||||||||||||||||||
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| Eigenschaften | |||||||||||||||||||
| Molare Masse | 422,35 g·mol−1 | ||||||||||||||||||
| Aggregatzustand |
fest[3] | ||||||||||||||||||
| Schmelzpunkt |
266–268 °C (Zersetzung)[2] | ||||||||||||||||||
| Sicherheitshinweise | |||||||||||||||||||
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| Wenn nicht anders vermerkt, gelten die angegebenen Daten bei Standardbedingungen (0 °C, 1000 hPa). | |||||||||||||||||||
Mangiferin (oder auch Chinonin genannt) ist ein Xanthon-Derivat, genauer das 2-C-Glucosid von 1,3,6,7-Tetrahydroxyxanthon.
Vorkommen
Natürlich kommt Mangiferin in Pflanzen der Gattungen Aphloia (Aphloia theiformis) und Mangifera (Mangos, z. B. Mangifera indica) vor. Eine verwandte Verbindung ist das Neomangiferin C25H28O16 (CAS-Nummer: 64809-67-2).
Verwendung
Mangiferin (als Bestandteil von Extrakten aus Mangoblättern) wird in der traditionellen chinesischen Medizin eingesetzt.[4]
Literatur
- Zhang HY: Scavenging effect of chinonin on free radicals studied with quantum chemistry. In: Acta Pharmacologica Sinica. Band 20, Nr. 6, 1999, S. 555–558, PMID 10678153.
- K. Sanugul, T. Akao, Y. Li, N. Kakiuchi, N. Nakamura, M. Hattori: Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. In: Biological and Pharmaceutical Bulletin. Band 28, Nr. 9, 2005, S. 1672–1678, PMID 16141538.
Einzelnachweise
- ↑ Eintrag zu MANGIFERIN in der CosIng-Datenbank der EU-Kommission, abgerufen am 12. Dezember 2021.
- ↑ a b Hideaki Matsuda, Masashi Tokunaga, Hiroyasu Iwahashi, Shunsuke Naruto, Hideki Yagi, Takashi Masuko, Michinori Kubo: Studies on Palauan Medicinal Herbs. II. Activation of Mouse Macrophages RAW 264.7 by Ongael, Leaves of Phaleria cumingii (MEISN.) F. VILL. and Its Acylglucosylsterols. In: Biological and Pharmaceutical Bulletin. Band 28, Nr. 5, 2005, S. 929–933, doi:10.1248/bpb.28.929.
- ↑ a b c Datenblatt Mangiferin from Mangifera indica bark bei Sigma-Aldrich, abgerufen am 3. Februar 2018 (PDF).
- ↑ Mangiferin (Nanning Innovative Pharmaceutical Technology) ( vom 2. März 2008 im Internet Archive).
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