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CCL23

CCL23
[[Datei:|250x200px|CCL23]]
CCL23
Andere Namen
  • Chemokine (C-C Motif) Ligand 23
  • SCYA23
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 23
  • Myeloid Progenitor Inhibitory Factor 1
  • Macrophage Inflammatory Protein 3
  • CK-BETA-8
  • MPIF-1
  • Ckb-8
  • MIP-3
  • C6 Beta-Chemokine
  • Ckb-8-1
  • Hmrp-2a

Vorhandene Strukturdaten: 1G91

Eigenschaften des menschlichen Proteins
Masse/Länge Primärstruktur 120 Aminosäuren, 13411 Da
Bezeichner
Externe IDs
Vorkommen
Homologie-Familie Hovergen

CCL23 (englisch CC-chemokine ligand 23) ist ein Zytokin aus der Familie der CC-Chemokine.

Eigenschaften

CCL23 ist an Entzündungsprozessen beteiligt. Es ist chemotaktisch für ruhende T-Zellen und in geringerem Umfang auch für Neutrophile. CCL23 wird in der Lunge und in der Leber sowie in geringerem Umfang im Knochenmark und in der Plazenta gebildet.[1] Es wird durch Interleukin-4 induziert.[2]

Einzelnachweise

  1. ↑ Patel et al. Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors. J. Exp. Med. 185: 1163–1172, 1997.
  2. ↑ H. Novak, A. Müller, N. Harrer, C. Günther, J. M. Carballido, M. Woisetschläger: CCL23 expression is induced by IL-4 in a STAT6-dependent fashion. In: Journal of Immunology. Band 178, Nummer 7, April 2007, S. 4335–4341, PMID 17371990.

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