THRAP3
THRAP3 Identifikatori Aliasi THRAP3 Vanjski ID-jevi OMIM : 603809 MGI : 2442637 HomoloGene : 31289 GeneCards : THRAP3 Ontologija gena Molekularna funkcija • nucleotide binding • GO:0001105 transcription coactivator activity • GO:0001104 transcription coregulator activity • thyroid hormone receptor binding • phosphoprotein binding • core promoter sequence-specific DNA binding • GO:0001948, GO:0016582 vezivanje za proteine • nuclear receptor coactivator activity • ATP binding • vitamin D receptor binding • vezivanje sa RNK • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • signaling receptor activity Ćelijska komponenta • nuclear speck • mediator complex • exon-exon junction complex • nukleoplazma • Egzosom • jedro Biološki proces • androgen receptor signaling pathway • GO:0009373 regulation of transcription, DNA-templated • positive regulation of mRNA splicing, via spliceosome • rhythmic process • mRNA processing • intracellular steroid hormone receptor signaling pathway • regulation of alternative mRNA splicing, via spliceosome • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • nuclear-transcribed mRNA catabolic process • mRNA stabilization • Jednodnevni biološki ritam • Prerada RNK • positive regulation of circadian rhythm • transcription initiation from RNA polymerase II promoter • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi Vrste Čovjek Miš Entrez Ensembl UniProt RefSeq (mRNK) RefSeq (bjelančevina) Lokacija (UCSC) Chr 1: 36.22 – 36.31 Mb Chr 4: 126.16 – 126.2 Mb PubMed pretraga[ 3] [ 4] Wikipodaci
Protein 3 pridružen receptoru tireoidnog hormona jest protein koji je kod ljudi kodiran genom THRAP3 sa hromosoma 1 .[ 5]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 955 aminokiselina , a molekulska težina Da . 108 666[ 6]
10 20 30 40 50 MSKTNKSKSG SRSSRSRSAS RSRSRSFSKS RSRSRSLSRS RKRRLSSRSR SRSYSPAHNR ERNHPRVYQN RDFRGHNRGY RRPYYFRGRN RGFYPWGQYN RGGYGNYRSN WQNYRQAYSP RRGRSRSRSP KRRSPSPRSR SHSRNSDKSS SDRSRRSSSS RSSSNHSRVE SSKRKSAKEK KSSSKDSRPS QAAGDNQGDE AKEQTFSGGT SQDTKASESS KPWPDATYGT GSASRASAVS ELSPRERSPA LKSPLQSVVV RRRSPRPSPV PKPSPPLSST SQMGSTLPSG AGYQSGTHQG QFDHGSGSLS PSKKSPVGKS PPSTGSTYGS SQKEESAASG GAAYTKRYLE EQKTENGKDK EQKQTNTDKE KIKEKGSFSD TGLGDGKMKS DSFAPKTDSE KPFRGSQSPK RYKLRDDFEK KMADFHKEEM DDQDKDKAKG RKESEFDDEP KFMSKVIGAN KNQEEEKSGK WEGLVYAPPG KEKQRKTEEL EEESFPERSK KEDRGKRSEG GHRGFVPEKN FRVTAYKAVQ EKSSSPPPRK TSESRDKLGA KGDFPTGKSS FSITREAQVN VRMDSFDEDL ARPSGLLAQE RKLCRDLVHS NKKEQEFRSI FQHIQSAQSQ RSPSELFAQH IVTIVHHVKE HHFGSSGMTL HERFTKYLKR GTEQEAAKNK KSPEIHRRID ISPSTFRKHG LAHDEMKSPR EPGYKAEGKY KDDPVDLRLD IERRKKHKER DLKRGKSRES VDSRDSSHSR ERSAEKTEKT HKGSKKQKKH RRARDRSRSS SSSSQSSHSY KAEEYTEETE EREESTTGFD KSRLGTKDFV GPSERGGGRA RGTFQFRARG RGWGRGNYSG NNNNNSNNDF QKRNREEEWD PEYTPKSKKY YLHDDREGEG SDKWVSRGRG RGAFPRGRGR FMFRKSSTSP KWAHDKFSGE EGEIEDDESG TENREEKDNI QPTTE
Reference
Dopunska literatura
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