STOX1
Identifikatori
Aliasi	STOX1
Vanjski ID-jevi	OMIM: 609397 MGI: 2684909 HomoloGene: 17649 GeneCards: STOX1
Lokacija gena (čovjek) Hrom. Hromosom 10 (čovjek)[1] Bend 10q22.1 Početak 68,827,531 bp[1] Kraj 68,895,432 bp[1]
Lokacija gena (miš) Hrom. Hromosom 10 (miš)[2] Bend 10|10 B4 Početak 62,494,822 bp[2] Kraj 62,561,907 bp[2]
Ontologija gena Molekularna funkcija • vezivanje sa DNK • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • citoplazma • centrosom • nukleoplazma • centar organizacije mikrotubula • cell cortex • citoskelet • jedro • fibrillar center • Jedarce • citosol Biološki proces • positive regulation of protein kinase B signaling • GO:0009373 regulation of transcription, DNA-templated • regulation of mitochondrion organization • regulation of mitochondrial DNA metabolic process • positive regulation of epithelial cell proliferation • negative regulation of gene expression • transcription, DNA-templated • positive regulation of peptidyl-serine phosphorylation • positive regulation of cyclin-dependent protein kinase activity • Ćelijska dioba • regulation of mitochondrial membrane potential • GO:1901313 positive regulation of gene expression • positive regulation of cell cycle • positive regulation of peptidyl-threonine phosphorylation • positive regulation of cell population proliferation • regulation of transcription from RNA polymerase II promoter in response to hypoxia • regulation of response to oxidative stress • Regulacija ekspresije gena • inner ear development • positive regulation of G2/M transition of mitotic cell cycle • ćelijski ciklus • cellular response to nitrosative stress • positive regulation of otic vesicle morphogenesis • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	219736	216021
Ensembl	ENSG00000165730	ENSMUSG00000036923
UniProt	Q6ZVD7	B2RQL2
RefSeq (mRNK)	NM_001130159 NM_001130160 NM_001130161 NM_001130162 NM_152709	NM_001033260 NM_001364705
RefSeq (bjelančevina)	NP_001123631 NP_001123632 NP_001123633 NP_689922	NP_001028432 NP_001351634
Lokacija (UCSC)	Chr 10: 68.83 – 68.9 Mb	Chr 10: 62.49 – 62.56 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Rodasta kutija 1 je protein koji je kod ljudi kodiran genom STOX1.^[5]

Dužina polipeptidnog lanca je 989 aminokiselina, а molekulska težina 110.962 Da.^[6]

Protein kodiran ovim genom može funkcionirati kao protein koji veže DNK. Mutacije u ovom genu povezane su s preeklampsijom/eklampsijom 4 (PEE4). Za ovaj gen pronađene su alternativno prerađene varijante transkripta koje kodiraju različite izoforme (prema RefSeq, Sep 2009).