Protein jedarnog tijela SP14 jest protein koji je kod ljudi kodiran genom SP140 sa hromosoma 2.[5]
Amiokiselininska sekvenca
Dužina polipeptidnog lanca je 867 aminokiselina, a molekulska težina 98.223 Da.[6]
10 | | 20 | | 30 | | 40 | | 50 |
MAQQGQQGQM | | ASGDSNLNFR | | MVAEIQNVEG | | QNLQEQVCPE | | PIFRFFRENK |
VEIASAITRP | | FPFLMGLRDR | | SFISEQMYEH | | FQEAFRNLVP | | VTRVMYCVLS |
ELEKTFGWSH | | LEALFSRINL | | MAYPDLNEIY | | RSFQNVCYEH | | SPLQMNNVND |
LEDRPRLLPY | | GKQENSNACH | | EMDDIAVPQE | | ALSSSPRCEP | | GFSSESCEQL |
ALPKAGGGDA | | EDAPSLLPGG | | GVSCKLAIQI | | DEGESEEMPK | | LLPYDTEVLE |
SNGMIDAART | | YSTAPGEKQG | | EEEGRNSPRK | | RNQDKEKYQE | | SPEGRDKETF |
DLKTPQVTNE | | GEPEKGLCLL | | PGEGEEGSDD | | CSEMCDGEEP | | QEASSSLARC |
GSVSCLSAET | | FDLKTPQVTN | | EGEPEKELSL | | LPGEGEEGSD | | DCSEMCDGEE |
RQEASSSLAR | | RGSVSSELEN | | HPMNEEGESE | | ELASSLLYDN | | VPGAEQSAYE |
NEKCSCVMCF | | SEEVPGSPEA | | RTESDQACGT | | MDTVDIANNS | | TLGKPKRKRR |
KKRGHGWSRM | | RMRRQENSQQ | | NDNSKADGQV | | VSSEKKANVN | | LKDLSKIRGR |
KRGKPGTRFT | | QSDRAAQKRV | | RSRASRKHKD | | ETVDFKAPLL | | PVTCGGVKGI |
LHKKKLQQGI | | LVKCIQTEDG | | KWFTPTEFEI | | KGGHARSKNW | | RLSVRCGGWP |
LRWLMENGFL | | PDPPRIRYRK | | KKRILKSQNN | | SSVDPCMRNL | | DECEVCRDGG |
ELFCCDTCSR | | VFHEDCHIPP | | VEAERTPWNC | | IFCRMKESPG | | SQQCCQESEV |
LERQMCPEEQ | | LKCEFLLLKV | | YCCSESSFFA | | KIPYYYYIRE | | ACQGLKEPMW |
LDKIKKRLNE | | HGYPQVEGFV | | QDMRLIFQNH | | RASYKYKDFG | | QMGFRLEAEF |
EKNFKEVFAI | | QETNGNN |
Reference
Dopunska literatura
Vanjski linkovi
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Nuclear body protein SP140