Miozinski VIIA i Rab interaktivni protein jest protein koji je kod ljudi kodiran genom MYRIP sa hromosoma 3.[5]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 859 aminokiselina, а molekulska težina 95.706 Da.[6].
10 | | 20 | | 30 | | 40 | | 50 |
MGRKLDLSGL | | TDDETEHVLQ | | VVQRDFNLRK | | KEEERLSELK | | QKLDEEGSKC |
SILSKHQQFV | | EHCCMRCCSP | | FTFLVNTKRQ | | CGDCKFNVCK | | SCCSYQKHEK |
AWVCCVCQQA | | RLLRAQSLEW | | FYNNVKSRFK | | RFGSAKVLKN | | LYRKHRLESG |
ACFDILGGSL | | FESNLENEGS | | ISGSDSTFYR | | QSEGHSVMDT | | LAVALRVAEE |
AIEEAISKAE | | AYGDSLDKQN | | EASYLRDHKE | | ELTEELATTI | | LQKIIRKQKS |
KSEQQVEEEP | | GWPHPQSCST | | KVADEGTSAS | | PGGYRAPAAL | | WRSQSAFSIT |
GEEALKTPPV | | EAPSRQPRDQ | | GQHPRAESAL | | PSWKSVDRLD | | ETNLAPVLQS |
PDGNWVALKD | | GAPPPTRLLA | | KPKSGTFQAL | | EVASSVASAY | | DEMGSDSEED |
FDWSEALSKL | | CPRSRALPRN | | PQPQPTQAQS | | SDQGPIAASP | | SSALSPNPEA |
MCSDSETSSA | | GSSREVGHQA | | RLSWLQRKAP | | RNPAAEKMRL | | HGELDVNFNP |
QLASRETSDS | | SEPEEAPHTT | | DRRARRWRRA | | RLGSEEPSKE | | PSSPSAQLRD |
LDTHQVSDDL | | SETDISNEAR | | DPQTLTDTTE | | EKRRNRLYEL | | AMKMSEKETS |
SGEDQESEPK | | TESENQKESL | | SSEDNSQSVQ | | EELKKKFSAV | | SLCNISTEVL |
KVINATEELI | | AGSTGPWESP | | QVPPDRQKGM | | FPRGTDQVRL | | DEQLTSLEEN |
VYLAAGTVYG | | LETQLTELED | | AARCIHSGTD | | ETHLADLEDQ | | VATAAAQVHH |
AELQISDIES | | RISALTIAGL | | NIAPCVRFTR | | RRDQKQRTQV | | QTIDTSRQQR |
RKLPAPPVKA | | EKIETSSVTT | | IKTFNHNFIL | | QGSSTNRTKE | | RKGTTKDLME |
PALESAVMY |
Reference
Dopunska literatura
- El-Amraoui A, Schonn JS, Küssel-Andermann P, Blanchard S, Desnos C, Henry JP, Wolfrum U, Darchen F, Petit C (2002). "MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes". EMBO Rep. 3 (5): 463–70. doi:10.1093/embo-reports/kvf090. PMC 1084103. PMID 11964381.