LYAR
Jedarcetov protein regulacije ćelijskog rastaprotein koji je kod ljudi kodiran genom LYAR sa hromosoma 4 (reaktivni klonski antigen Ly-1).[ 5]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 379 aminokiselina , а molekulska težina 43.615 Da .[ 6]
10 20 30 40 50 MVFFTCNACG ESVKKIQVEK HVSVCRNCEC LSCIDCGKDF WGDDYKNHVK CISEDQKYGG KGYEGKTHKG DIKQQAWIQK ISELIKRPNV SPKVRELLEQ ISAFDNVPRK KAKFQNWMKN SLKVHNESIL DQVWNIFSEA SNSEPVNKEQ DQRPLHPVAN PHAEISTKVP ASKVKDAVEQ QGEVKKNKRE RKEERQKKRK REKKELKLEN HQENSRNQKP KKRKKGQEAD LEAGGEEVPE ANGSAGKRSK KKKQRKDSAS EEEAHVGAGK RKRRHSEVET DSKKKKMKLP EHPEGGEPED DEAPAKGKFN WKGTIKAILK QAPDNEITIK KLRKKVLAQY YTVTDEHHRS EEELLVIFNK KISKNPTFKL LKDKVKLVK
Funkcija
LYAR sadrži motiv cinkovog prsta i tri kopije nukleolusnih signala. LYAR se uglavnom nalazi na jedarcima, u visokim nivoima u ranim embrionima i prvenstveno u jetri i fetusnom timusu .[ 7]
Reference
Dopunska literatura
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