In October 2004, it was announced that "You and I" would be the theme of Air Canada's new advertising campaign. At the same time the airline unveiled new in-flight service products and new aircraft livery. Dion also recorded a one-minute-long French version of the song called "Mes ailes à moi." Both versions were used in Air Canada's commercials.
The single was a radio hit, topping the Canadian Adult Contemporary Chart for five non-consecutive weeks in July and August 2004, and spending 34 weeks on the chart in total.[2]
Chuck Taylor of Billboard magazine wrote about the song: "The plucky "You and I" is an ideal vehicle to launch a full-scale seasonal assault on the airwaves, with its love-my-man thematics and kinetic, summer-breeze tempo, akin to her signature "That's the Way It Is." Dion dispenses a joyful romp from the mic, sounding fresh and fully at ease, and she riffs just enough to stamp the song with a telltale trademark or two."