William R. Brinkley

For other uses, see William Brinkley (disambiguation).

William R. "Bill" Brinkley, was an American cellular biologist and scientific advocate[1] and served as a Professor and Dean of the Graduate School of Biomedical Sciences at Baylor College of Medicine. Brinkley was recognized particularly for contributing to discovery of the attachment of chromosomes to the mitotic spindle apparatus.

Biography

Brinkley earned his undergraduate degree in general biology from Sam Houston State University, where he later taught biology and maintained the school's small natural history museum.[2] He then earned a master's degree in biology, under Dr. James "Jimmy" Long, working with mosquitoes. He earned his PhD in the lab of John H. D. Bryan at Iowa State University in 1964, followed by NIH post-doctoral training with Tao-Chiuh Hsu at The University of Texas MD Anderson Cancer Center and an assistant and associate professor of biology until 1972, when he accepted a position as Professor and Director of Cell Biology in the Department of Human Biological Chemistry at the University of Texas Medical Branch at Galveston, Texas.[1]

In 1966, Brinkley was the first to characterize and visualize the kinetochore, a complex protein structure that guides chromosomes to split evenly between daughter cells during mitosis and meiosis.[3] He continues to make key contributions in cellular replication and developmental biology, and was honored in a dedicated FASEB meeting titled the "Brinkley-Fest of Mitosis" in 2007.[3] Brinkley passed away on 10 November 2020, at the age of 84.[4]

Research focus

Brinkley is attempting to uncover the molecular basis of errors and defects in the nucleus and mitotic apparatus that cause aneuploidy.

Memberships and awards

Brinkley has served on numerous journal editorial boards including Journal of Cell Biology and Cell. He briefly served as president of the American Society for Cell Biology (1979–1980). He was the recipient of a Merit Award from the National Institutes of Health, National Cancer Institute, for his research on cell division and genomic instability in tumor cells. He served as President of Federation of American Societies for Experimental Biology from 1998 to 1999.He currently serves on the board of the Genetics Policy Institute. He was a member of the Institute of Medicine and is recognized as a Distinguished Alumnus from Sam Houston State University, Iowa State University, and The University of Texas M. D. Anderson Cancer Center. In 2014, he received the highest honor from the American Society for Cell Biology, the E.B. Wilson Medal.[5]

References

  1. ^ a b http://www.researchamerica.org/brinkley_william Archived 2008-04-24 at the Wayback Machine Research America biography profile
  2. ^ "Friends Honor Alumnus With Scholarship". Communications Office, Sam Houston State University, (SHSU). 2011. Retrieved 2018-11-19.
  3. ^ a b Heald, Rebecca (2007). "Brinkley-Fest of Mitosis". Developmental Cell. 13 (2): 168–76. doi:10.1016/j.devcel.2007.07.010. PMID 17681129.
  4. ^ Garrison, Howard H.; Masters, Bettie Sue; Bond, Judith (2021-03-30). "William R. Brinkley (1936–2020)". FASEB BioAdvances. 3 (4): 280–281. doi:10.1096/fba.2021-00034. ISSN 2573-9832. PMC 8019260.
  5. ^ Fleischman, John (2014). "Giants of the Cytoskeleton Win E.B. Wilson Medal". American Society for Cell Biology. Retrieved May 10, 2017.

Scientific Lineage

Read other articles:

Andrew Rannells

Andrew RannellsRannells tahun 2015LahirAndrew Scott Rannells23 Agustus 1978 (umur 45)[1]Omaha, Nebraska, Amerika Serikat[1]PekerjaanAktorTahun aktif1995–sekarang Andrew Scott Rannells (lahir 23 Agustus 1978) adalah seorang aktor film, teater, televisi dan pengisi suara asal Amerika Serikat. Rannells dikenal karena berperan sebagai Elder Kevin Price dalam musikal Broadway 2011 The Book of Mormon di mana dia dinominasikan untuk Penghargaan Tony untuk Penampilan Terb...

 

Zivanna Letisha Siregar

Ini adalah nama Batak Angkola, marganya adalah Siregar. Zivanna Letisha SiregarZivanna di Qur'an Indonesia ProjectLahirZivanna Letisha Siregar16 Februari 1989 (umur 35)Jakarta, IndonesiaNama lainZivanna LetishaZiziPekerjaanModel, Ratu kecantikan, Penulis, Filantropis, PresenterTahun aktif2008 - sekarangTinggi178 cm (5 ft 10 in)Suami/istriHaries Argareza Harahap ​ ​(m. 2016)​Anak3 Zivanna Letisha SiregarPemenang kontes kecantikan...

 

Roman Catholic Archdiocese of Newark

Catholic archdiocese in the United States Archdiocese of NewarkArchidiœcesis NovarcensisCathedral Basilica of the Sacred HeartCoat of Arms of the Archdiocese of NewarkLocationCountry United StatesTerritoryCounties of Bergen, Essex, Hudson and Union, New JerseyEcclesiastical provinceNewarkHeadquartersNewark, New JerseyStatisticsArea1,328 km2 (513 sq mi)Population- Total- Catholics(as of 2016)3,179,2761,469,295 (46.2%)InformationDenominationRoman CatholicSui ...

Seigny

Ne doit pas être confondu avec Ségny. Cet article est une ébauche concernant une commune de la Côte-d'Or. Vous pouvez partager vos connaissances en l’améliorant (comment ?). Le bandeau {{ébauche}} peut être enlevé et l’article évalué comme étant au stade « Bon début » quand il comporte assez de renseignements encyclopédiques concernant la commune. Si vous avez un doute, l’atelier de lecture du projet Communes de France est à votre disposition pour vous ai...

 

Rudolf von Jhering

German jurist (1818–1892) For zoologist, see Hermann von Ihering. This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article relies largely or entirely on a single source. Relevant discussion may be found on the talk page. Please help improve this article by introducing citations to additional sources.Find sources: Rudolf von Jhering – news · newspapers · ...

 

Первородный грех

Об экономическом термине см. Первородный грех (экономика). ХристианствоБиблия Ветхий Завет Новый Завет Евангелие Десять заповедей Нагорная проповедь Апокрифы Бог, Троица Бог Отец Иисус Христос Святой Дух История христианства Апостолы Хронология христианства Ран�...

Walter Kirn

Walter KirnKirn pada 1 Maret 2015Lahir3 Agustus 1962 (umur 61)Akron, Ohio, Amerika SerikatTempat tinggalLivingston, Montana, ASLos Angeles, California, ASKebangsaanAmerikaAlmamaterPrinceton University, Oxford UniversityPekerjaanNovelis, kritikus sastra, pembuat esayKarya terkenalUp in the AirSuami/istriPenelope Locke (bercerai)Maggie McGuane (bercerai)Amanda FortiniAnak2 Walter Kirn (lahir 3 Agustus 1962)[1] adalah seorang novelis, kritikus sastra, dan esayis asal Amerika Serika...

 

Zwolle

Zwolle Hanseatic city (en)munisipalitas di Belandakota besarcadastral populated place in the Netherlands (en)place with town rights and privileges (en) Zwolle (nl) flag of Zwolle (en) coat of arms of Zwolle (en) dan first coat of arms of Zwolle (en) Tempat Negara berdaulatKerajaan BelandaCountry of the Kingdom of the Netherlands (en)BelandaProvinsi di BelandaOverijssel Ibu kota dariOverijssel NegaraBelanda Pembagian administratifWindesheim (en) Brinkhoek (en) Harculo (en) Wijthmen (en) Brugge...

 

Yokosuka

Cet article est une ébauche concernant une localité japonaise. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Yokosuka-shi 横須賀市 Vue de Yokosuka depuis le parc Verny. Drapeau Administration Pays Japon Région Kantō Préfecture Kanagawa Maire Katsuaki Kamiji Code postal 〒238-8550 Démographie Population 394 698 hab. (octobre 2018) Densité 3 915 hab./km2 Géographie Coordonnées 3...

Fire plough

Firelighting tool A fire plough in Vanuatu. A fire plough (left), as opposed to a hand drill (right). A fire plough (or fire plow) is a firelighting tool. In its simplest form, it is two sticks rubbed together.[1] Rubbing produces friction and heat, and eventually an ember.[2] More advanced are stick-and-groove forms, which typically uses a V-shaped base piece of wood, and a friction stick as the activator.[2][3] The typical fire plough consists of a stick cut ...

 

David Tennant

For other people named David Tennant, see David Tennant (disambiguation). Scottish actor (born 1971) David TennantTennant in 2023BornDavid John McDonald (1971-04-18) 18 April 1971 (age 53)Bathgate, ScotlandEducationRoyal Conservatoire of Scotland (BA)OccupationActorYears active1987–presentKnown forTenth incarnation of the Doctor in Doctor WhoSpouse Georgia Moffett ​(m. 2011)​Children5, including TyRelativesSandy McDonald (father)Archie McLeod (gra...

 

Reggianito

Argentine cheese ReggianitoCountry of originArgentinaSource of milkPasture-fed cowsTextureHard, granularAging time6 months Reggianito is an Argentine cheese that is a very hard, granular, cow's milk cheese. The cheese was developed by Italian immigrants to Argentina who wished to make a cheese reminiscent of their native Parmigiano Reggiano. The name—the Spanish diminutive of Reggiano—refers to the fact that the cheese is produced in small 6.8 kg (15 lb) wheels, rather than the ...

Ubisoft Leamington

British video game developer Ubisoft LeamingtonFormerlyFreeStyleGames Limited (2002–2017)Company typeSubsidiaryIndustryVideo gamesFounded29 November 2002; 21 years ago (2002-11-29) in Warwick, EnglandFounderAlex DarbyAlex ZoroDavid OsbournJamie JacksonJonny AmbrosePhil HindleHeadquartersLeamington Spa, EnglandKey peopleLisa Opie (managing director)ProductsDJ Hero seriesGuitar Hero seriesNumber of employees50 (2016)ParentActivision (2008–2017)Ubisoft (2017–present)...

 

Stasiun Tanggulangin

Untuk kegunaan lain, lihat TGA. Artikel ini bukan mengenai Stasiun Tanggul. Stasiun Tanggulangin P15T15SP15 Stasiun Tanggulangin pada tahun 2020Lokasi Jalan Raya Tanggulangin / Surabaya–MalangKalitengah, Tanggulangin, Sidoarjo, Jawa Timur 61272IndonesiaKoordinat7°30′24.998″S 112°42′29.002″E / 7.50694389°S 112.70805611°E / -7.50694389; 112.70805611Koordinat: 7°30′24.998″S 112°42′29.002″E / 7.50694389°S 112.70805611°E / -...

 

نجيب ميقاتي

نجيب ميقاتي رئيس وزراء لبنان تولى المنصب10 سبتمبر 2021 الرئيس ميشيل عون النائب سعادة الشامي حسان دياب   رئيس وزراء لبنان الـ 48 في المنصب13 يونيو 2011 – 15 فبراير 2014 الرئيس ميشال سليمان سعد الدين الحريري تمام سلام رئيس وزراء لبنان الـ 45 في المنصب19 أبريل 2005 – 19 يوليو 2005 الرئيس إم�...

The 34th Rule

1999 novel by Armin Shimerman and David R. George III For other uses, see Rule 34 (disambiguation). The 34th Rule The cover of The 34th RuleAuthorArmin ShimermanDavid R. George IIICountryUnited StatesLanguageEnglishSubjectStar Trek: Deep Space NineGenreScience fictionPublisherPocket BooksPublication dateJanuary 1, 1999 (1999-01-01)Pages288ISBN0-671-00793-9 The 34th Rule (ISBN 0-671-00793-9), published January 1, 1999, is a Star Trek: Deep Space Nine novel written by Armin ...

 

Wartime sexual violence

Acts of sexual violence committed by combatants during armed conflict, war or military occupation Monument to the Condottiero Giovanni dalle Bande Nere depicting a man kidnapping a woman (Piazza San Lorenzo, Florence) Part of a series onWarOutline History Prehistoric Ancient Post-classical castles Early modern pike and shot napoleonic Late modern industrial fourth-gen Military Organization Command and control Defense ministry Army Navy Air force Marines Coast guard Space force Reserves Regula...

 

Tarzana, Los Angeles

Neighborhood of Los Angeles, California Neighborhood of Los Angeles in California, United StatesTarzana, Los AngelesNeighborhood of Los AngelesTarzanaMulholland Park Gate in Tarzana in 2007Location of Tarzana (highlighted in blue) in Los AngelesTarzana, Los AngelesLocation of Tarzana in Los Angeles and the San Fernando ValleyShow map of San Fernando ValleyTarzana, Los AngelesTarzana, Los Angeles (the Los Angeles metropolitan area)Show map of the Los Angeles metropolitan areaTarzana, Los Angel...

Howdy Doody

American children's television series (1947–1960) Howdy DoodyBuffalo Bob Smith and Howdy Doody in 1972GenreChildren's television seriesCreated byE. Roger MuirPresented by Buffalo Bob Smith Howdy Doody Starring Bob Keeshan Lew Anderson Bobby Nicholson Country of originUnited StatesProductionProducersE. Roger Muir and Nick NicholsonRunning time 60 minutes (1947–1948, 1960) 30 minutes (1948–1960) Original releaseNetworkNBCReleaseDecember 27, 1947 (1947-12-27) –September 24, 196...

 

Lorenteggio

Lorenteggio Stato Italia Regione Lombardia Provincia Milano Città Milano CircoscrizioneMunicipio 6 Altitudine118 m s.l.m. Abitanti6 000 ab. Nome abitantilorenteggesi LorenteggioLorenteggio (Milano) Lorenteggio (Lorentegg[1] in dialetto milanese, AFI: [luˌrẽːˈted͡ʒ]), è un quartiere di Milano, posto a sud-ovest rispetto al centro, appartenente al Municipio 6. Indice 1 Origini del nome 2 Storia 3 Monumenti e luoghi d'interesse 3.1 Architetture religiose...