Paul Hamilton was laid down 20 January 1943 by the Charleston Navy Yard; launched 7 April 1943; sponsored by Mrs. William Dewar Gordon; and commissioned 25 October 1943.
From 1 September to 3 October, Paul Hamilton served as a screening vessel for the replenishment aircraft and fueling groups that serviced the 3d Fleet during the capture of the southern Palau Islands. She played a similar role for the 3d Fleet 4 October to 15 November during air strikes against Okinawa, Luzon, Formosa, the Visayan Islands, and the Japanese fleet.
She proceeded via Hollandia, New Guinea, to Leyte Gulf, Philippines, where she patrolled 7 to 11 December to protect shipping from enemy surface attacks. She screened for the amphibious assault force that landed on Mindoro Island, Philippines, 15 December, and shot down three enemy planes that day. From 27 December to 2 January 1945 she screened ships resupplying U.S. Army forces on Mindoro.
From 3 to 21 January, Paul Hamilton screened for the assault on Lingayen Gulf, Philippines. She rescued 73 survivors from Ommaney Bay (CVE-79) on the 4th.
She departed Okinawa 17 June 1945, and proceeded via Guam, Eniwetok, and Pearl Harbor to San Diego, Calif. where she arrived 8 July for overhaul. Paul Hamilton reported to the Pacific Reserve Fleet 24 September 1945 and remained inactive until struck from the Naval Vessel Register 1 May 1968. She was sold 2 April 1970 and broken up for scrap.