Leslie Smith was expected to face Raquel Pennington at this event. However, Smith was forced to pull out of the event due to injury and Pennington was rebooked against a separate opponent at another event.[5][6]
Johny Hendricks was set to face Tyron Woodley in the co-main event. However, Hendricks pulled out of the fight on the day of the weigh-ins due to a kidney stone and intestinal blockage suffered during his weight cut. Therefore, the fight was canceled.[9]
Francisco Treviño missed weight on his first attempt at the weigh ins, coming in at 160 lb. He was given additional time to make the weight limit, but made no attempts to cut further. Instead, he was fined 20 percent of his fight purse, which went to Sage Northcutt.[10]
On October 15, it was announced that Treviño tested positive for marijuana in post-fight tests. If Treviño was found by the Texas Department of Licensing and Regulation's enforcement division to have violated its rules, he would face a one-year probated suspension, in which he can still fight provided he does not break any more rules, or a full one-year suspension. He also faced up to a $5,000 fine.[11]