In 1596 it appeared as a large village in the tax registers under the name of Sitan, as being in the nahiya ("subdistrict") of Ramla, which was under the administration of the liwa ("district") of Gaza. It had a population of 123 households who were all Muslims.[5] They paid a fixed tax-rate of 33,3 % on agricultural products, including wheat, barley, summer crops, sesame, vineyards, fruit trees, goats and beehives, in addition to occasional revenues; a total of 19,100 akçe. All of the revenue went to a Waqf.[6] Archaeological excavations found settlement remains from this period, including walls, floors, cooking ovens and a rich ceramic repertoire.[2][3]
In 1051 AH/1641/2, the Bedouin tribe of al-Sawālima from around Jaffa attacked the villages of Subtara, Bayt Dajan, al-Sāfiriya, Jindas, Lydda and Yazur belonging to Waqf Haseki Sultan. Under nomadic pressures, Subṭāra was abandoned and its residents moved to Kafr 'Ana, than a minor and insignificant hamlet.[7]
During the 18th and 19th centuries, the area around Subtara now belonged to the Nahiyeh (sub-district) of Lod that encompassed the area of the present-day city of Modi'in-Maccabim-Re'ut in the south to the present-day city of El'ad in the north, and from the foothills in the east, through the Lod Valley to the outskirts of Jaffa in the west. This area was home to thousands of inhabitants in about 20 villages, who had at their disposal tens of thousands of hectares of prime agricultural land. The lands of Subtara were subsumed by the village of al-Safiriyya.[8]