He was taught classical music by his father and participated in nearly one hundred foreign music festivals. According to a major newspaper of India, "[Sharafat Ali Khan] had enormous grip over thumri, kafi, khayal and ghazal".[1] He also used to deliver lecturers on classical music at various universities.[3]
He was suffering from diabetes mellitus and hypertension and was bedridden for over three months and died late Monday on 30 November 2009 in Lahore, Pakistan at age 54 and is buried at the Charagh Shah Wali shrine, a cemetery in Lahore where his parents, grandmother and his father Salamat Ali Khan, two uncles Ustad Nazakat Ali Khan and Ustad Zakir Ali Khan are also buried.[3][1]