Howe was born in 1983 in Hong Kong. Her father is English; her mother was born in China, but left the country in 1949 for Hong Kong. The family moved to the UK in 1991, when Howe was aged seven.[3][4][5][6] Her first degree was in English at Christ's College, Cambridge, matriculating in 2001. She subsequently gained a PhD at that college; her thesis is entitled "Literature and the Visual Imagination in Renaissance England, 1580–1620".[7][8] During her studies, she spent a year at Harvard University, with a Kennedy Scholarship; it was there that she began to write poetry seriously at the age of around 21.[5][8][9]
She spent five years as a research fellow at the Faculty of English and Gonville and Caius College, Cambridge, until 2015.[8][10] Her research there was in the area of 16th- and 17th-century English literature; her interests included relationships between poetry and visual art forms, including sculpture and architecture.[8] In 2014, Howe founded the online poetry journal Prac Crit, and she continues to serve as one of its editors.[11][12]
Her first collection, Loop of Jade, was published by Chatto & Windus in 2015.[3] It explores Howe's British and Chinese heritage,[4] and in particular her mother's history as an abandoned female baby in China.[16] The main sequence of poems is inspired by Jorge Luis Borges's fictional encyclopedia, The Celestial Emporium of Benevolent Knowledge.[17][18]
As of 2015–16, Howe was working on a sequence called Two Systems, which examines China's interaction with the West and the recent history of Hong Kong, in particular the pro-democracy Umbrella Movement. The work uses techniques that include the incorporation of found documents, such as the constitution of Hong Kong, reworked by erasing material.[9][13]
Her poetry has appeared in several anthologies, including three editions of The Best British Poetry (Salt), Dear World & Everyone in It: New Poetry in the UK (Bloodaxe; 2013) and Ten: The New Wave (Bloodaxe; 2014).[5][13][17] Her sonnet "Relativity", commissioned for the 2015 National Poetry Day, was recorded by physicist Stephen Hawking, also a fellow of Gonville and Caius College. His book A Brief History of Time had inspired Howe as a teenager.[4][21][22]