Molecular design of natural and synthetic lipids and membranes for gene delivery and synthesis of novel peptides and for sequence-specific DNA recognition. Synthesis of unnatural amino acids, DNA binding small molecules, and biologically active natural products
Focusing his researches at the interfaces of chemistry, biology, materials science and nanotechnology, Bhattacharya is reported to have made notable contributions in the design and synthesis of lipids, gene delivery vehicles, soft matter, molecular bioanalytic sensors, unnatural amino acids and oligopeptides, G-quadruplex and Duplex-DNA binding small molecules as putative therapeutics, and other biologically active natural product mimics.[12] He has carried out several projects which include lipid molecular design and biophysics, peptide designs, structural studies of micelles, DNA binding anti-cancer agents,[13] and design and synthesis of nanomaterials.[3] He has published his researches by way of several peer-reviewed articles;[14] the online repository of the Indian Academy of Sciences has listed 117 of them.[15] On the academic administration front, he established a laboratory for bio-organic and supramolecular studies at Indian Institute of Science. He has supervised the post-graduate, doctoral and post-doctoral studies of several scholars and has sat in the editorial boards of journals such as Bioconjugate Chemistry and Langmuir of American Chemical Society, and the Journal of Materials Nanoscience.[10]
Awards and honors
Bhattacharya received the B. M. Birla Science Award in 1997[16] Swarnajayanti Fellowship Award (DST) in 1998, the Materials Research Society of India Medal in 1999 and the Chemical Research Society of India Bronze Medal in 2000.[3] The Department of Biotechnology awarded him with the National Bioscience Award for Career Development in 2002 [7] and the Council of Scientific and Industrial Research awarded him in 2003 with the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards.[17] He received the TWAS Prize in 2010[8] the Ranbaxy Research Award in 2013 and SASTRA-CNR Rao Award in 2017.[10] P. U. Bhagyatara National Award (2004), CDRI Award of the Central Drug Research Institute (2004) and the G. D. Birla Award (2007) are some of the other notable awards he has received.[3] Holder of J. C. Bose National Fellowship in 2008 and Swarna Jayanti Fellowship of the Department of Science and Technology during 1998–2003, he was elected as a fellow by the Indian Academy of Sciences in 2000[5] and he became an elected fellow of the Indian National Science Academy in 2007 and The World Academy of Sciences in 2012.[4] He has also delivered several award orations including the D. Ranganathan Memorial Lecture of the Chemical Research Society of India (2007) and the Nitya Anand Endowment Lecture of the Indian National Science Academy (2007).[3]
^Maji, Basudeb (2014). "Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA". Chem Commun. 50 (49): 6422–38. doi:10.1039/c4cc00611a. PMID24695755.