Picloxydine

Picloxydine
Names
IUPAC name
1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.024.623 Edit this at Wikidata
UNII
  • InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) ☒N
    Key: YNCLPFSAZFGQCD-UHFFFAOYSA-N ☒N
  • InChI=1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)
    Key: YNCLPFSAZFGQCD-UHFFFAOYAM
  • C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
Properties
C20H24Cl2N10
Molar mass 475.37756
Pharmacology
S01AX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Picloxydine (trade name Vitabact[1]) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine.

References

  1. ^ Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma". Revue Internationale du Trachome et de Pathologie Oculaire Tropicale et Subtropicale et de Santé Publique. 65 (3–4): 119–32. PMID 3274675.


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