In 1994 she wrote and directed the film Iavnana, which won her the State Prize of Georgia and Jakob Gogebashvili pedagogical prize.[2]
In 2000 Janelidze and actress Nanuka Khuskivadze founded the film production studio N&N.[3] In 2008-2009 Janelidze managed a project in which N&N studios collaborated with the Association for Film Heritage Protection to restore the 1912 film Journey of Akaki Tsereteili to Racha-Lechkhumi, Georgia's first documentary film.[4]
In 2011 Janelidze directed and co-wrote the film Will There Be a Theatre Up There?!, starring Kakhi Kavsadze, based on the true life story of the Kavsadze family. The film won a Nika Award for Best Film of the CIS and Baltic States.[3]
In 2012 she began presenting a cinema program on Folk-Radio. From 2013 to 2016 she was the director of the Georgian National Film Centre.[2]
In 2019 a teaser was released of a biographical film on the life of Ukrainian poet Lesya Ukrainka, directed by Janelidze, in a co-production between Georgia and Ukraine.[5]