NS-398

NS-398
Space-filling model of the NS-398 molecule
Names
Preferred IUPAC name
N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
  • InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 checkY
    Key: KTDZCOWXCWUPEO-UHFFFAOYSA-N ☒N
  • InChI=1/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3
    Key: KTDZCOWXCWUPEO-UHFFFAOYAY
  • CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2
Properties
C13H18N2O5S
Molar mass 314.36 g·mol−1
Appearance Off-white solid
Insoluble
Solubility in DMSO 5 mg/mL
Hazards
GHS labelling:[1]
GHS07: Exclamation mark
Warning
H302, H312, H332
P280
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.[2]

See also

References

  1. ^ "N194 NS-398". Sigma-Aldrich. Retrieved 13 December 2021.
  2. ^ Wei Shen; Yong Li; Ying Tang; James Cummins; Johnny Huard (2005). "NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis". American Journal of Pathology. 167 (4): 1105–1117. doi:10.1016/S0002-9440(10)61199-6. PMC 1603662. PMID 16192645.
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