In enzymology, a methyl-ONN-azoxymethanol beta-D-glucosyltransferase (EC 2.4.1.171) is an enzyme that catalyzes the chemical reaction

UDP-glucose + methyl-ONN-azoxymethanol ${\displaystyle \rightleftharpoons }$ UDP + cycasin

Thus, the two substrates of this enzyme are UDP-glucose and methyl-ONN-azoxymethanol, whereas its two products are UDP and cycasin.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase. Other names in common use include cycasin synthase, uridine diphosphoglucose-methylazoxymethanol glucosyltransferase, and UDP-glucose-methylazoxymethanol glucosyltransferase.

• Tadera K, Yagi F, Arima M, Kobayashi A (1985). "Formation of cycasin from methylazoxymethanol by UDP-glucosyltransferase from leaves of Japanese cycad". Agric. Biol. Chem. 49 (9): 2827–2828. doi:10.1271/bbb1961.49.2827.