Kyowa Kirin

Kyowa Kirin Co., Ltd.
Company typePublic (K.K)
TYO: 4151
Nikkei 225 Component
Industry
FoundedJuly 1, 1949; 75 years ago (1949-07-01)
HeadquartersOhtemachi Building, 1-6-1, Ōtemachi, Chiyoda-ku, Tokyo 100–8185, Japan
Key people
Nobuo Hanai, (CEO and President)
Products
Revenue$ 2.99 billion USD (FY 2022) Increase (¥ 398.4 billion JPY) (FY 2022)
$ 375 million USD (FY 2022) Increase (¥ 53.6 billion JPY) (FY 2022)
Number of employees
7,532 (consolidated) (as of December 31, 2017)
ParentKirin Holdings Company, Limited
Subsidiaries47 (33 in Japan and 14 overseas countries)
WebsiteOfficial website
Footnotes / references
[1][2][3]

Kyowa Kirin Co., Ltd. (協和キリン株式会社, Kyōwa Kirin Kabushiki Kaisha) is a Japanese pharmaceutical and biotechnology company under the Kirin Holdings, and is among the 40 largest in the world by revenue. The company is headquartered in Chiyoda-ku, Tokyo and is a member of the Nikkei 225 stock index.[4][5]

History

On July 1, 1949 the forerunner of the present company, Kyowa Hakko Kogyo Co., Ltd. is established. Following the merger with Kirin Pharma Co., Ltd., on October 1, 2008 the company changed its name to its present.

On July 11, 2014, the KHK subsidiary, ProStrakan Group (based in Scotland), acquired Archimedes Pharma from the Novo Nordisk Foundation for $394 million [6]

In 2019, Kirin Holdings acquired 95% stake in Kyowa Hakko Bio which is Kyowa Kirin's subsidiary corporation.[7] The entity was renamed "Kyowa Kirin Co., Ltd.", replacing its prior name of Kyowa Hakko Kirin Co., Ltd.

In November 2022, Kyowa Kirin announced plans to spin its international established medicines portfolio into a new joint venture with German company Grünenthal.[8]

In October 2023, Kyowa Kirin acquired a Britain-based biopharmaceutical company, Orchard Therapeutics, for $478 million.[9]

Business segments and products

  • Pharmaceuticals business

The company developed a method to make afucosylated monoclonal antibodies using a CHO cell line in which FUT8 has been knocked out; the company calls this its "Potelligent" platform. The company gained marketing approval in Japan in April 2012 for a monoclonal antibody drug called mogamulizumab which was developed using the platform.[10]

References

  1. ^ "Kyowa Hakko Kirin Company Overview". Kyowa Hakko Kirin. Retrieved March 14, 2014.
  2. ^ "Kyowa Hakko Kirin Corporate Profile" (PDF). Kyowa Hakko Kirin. Retrieved March 14, 2014.
  3. ^ "Kyowa Hakko Kirin Annual Report 2012". Kyowa Hakko Kirin. Retrieved March 14, 2014.
  4. ^ "Components:Nikkei Stock Average". Nikkei Inc. Retrieved January 20, 2015.
  5. ^ "Top 50 Pharma Companies by 2012 Revenue". Wildwood Ventures Ltd. Archived from the original on February 8, 2014. Retrieved March 14, 2014.
  6. ^ "ProStrakan Acquires Archimedes Pharma for $394M". Genetic Engineering & Biotechnology News. Mary Ann Liebert, Inc. July 11, 2014. Retrieved January 20, 2015.
  7. ^ REYES, JEAN (6 February 2019). "Kirin to acquire 95% stake in Kyowa Hakko Bio".
  8. ^ "Grünenthal and Kyowa Kirin International Announce Joint Venture Collaboration for Established Medicines Portfolio". www.businesswire.com. 2022-11-24. Retrieved 2022-11-29.
  9. ^ "Kyowa Kirin to acquire Orchard Therapeutics for $478 million". Reuters. 2023-10-05. Retrieved 2023-10-05.
  10. ^ Yu, X; Marshall, MJE; Cragg, MS; Crispin, M (June 2017). "Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering" (PDF). BioDrugs. 31 (3): 151–166. doi:10.1007/s40259-017-0223-8. PMID 28466278. S2CID 3722081.
  11. ^ "FY 2013 Consolidated Financial Summary". Kyowa Hakko Kirin. Archived from the original on March 4, 2016. Retrieved March 14, 2014.

Read other articles:

Clemence Dane

Winifred AshtonLahir21 Februari 1888Blackheath, InggrisMeninggal28 Maret 1965(1965-03-28) (umur 77)London, InggrisNama penaClemence DanePekerjaanNovelist, pengarang dramaKarya terkenalRegiment of Women (1917) Clemence Dane adalah pseudonim dari Winifred Ashton (21 Februari 1888 – 28 Maret 1965), seorang novelis dan pengarang drama Inggris. Kehidupan dan karier Setelah menyelesaikan pendidikannya, ia datang ke Swiss untuk bekerja sebagai guru bahasa Prancis, namu...

 

Seven Keys to Baldpate (film 1925)

Seven Keys to BaldpateProduser-bintang Douglas MacLean dalam Seven Keys to BaldpateSutradaraFred C. NewmeyerProduserAdolph ZukorJesse LaskyDouglas MacLeanDitulis olehWade Boteler (skenario)Frank Griffin (skenario)BerdasarkanSeven Keys to Baldpateoleh Earl Derr Biggers (novel) dan George M. Cohan (sandiwara)PemeranDouglas MacLeanSinematograferJack MacKenzieDistributorParamount PicturesTanggal rilis 19 Oktober 1925 (1925-10-19) Durasi66 menit; 7 rol (6.648 feet)NegaraAmerika SerikatBahasaB...

 

Francisco Goya

Spanish painter and printmaker (1746–1828)Goya redirects here. For the food company, see Goya Foods. For other uses, see Goya (disambiguation). In this Spanish name, the first or paternal surname is de Goya and the second or maternal family name is Lucientes. Francisco de GoyaPortrait of Goya by Vicente López (1826), Museo del Prado, MadridBornFrancisco José de Goya y Lucientes(1746-03-30)30 March 1746Fuendetodos, Aragon, SpainDied16 April 1828(1828-04-16) (aged 82)Bordeaux, ...

Stellar atmosphere

Outer region of the volume of a star Photo taken in France during the 1999 solar eclipse The stellar atmosphere is the outer region of the volume of a star, lying above the stellar core, radiation zone and convection zone. Overview The stellar atmosphere is divided into several regions of distinct character: The photosphere, which is the atmosphere's lowest and coolest layer, is normally its only visible part.[1] Light escaping from the surface of the star stems from this region and p...

 

Lambang Antigua dan Barbuda

Lambang negara Antigua dan Barbuda adalah lambang resmi dari Antigua dan Barbuda. Format terkini lambang ini diresmikan pada 16 Februari 1967, didesain oleh Gordon Cristopher. Struktur Simbolisme lambang ini lebih lengkap daripada yang ditemui di bendera Antigua dan Barbuda, tetapi banyak elemen yang sama. Di atas lambang adalah nenas, buah khas pulau tersebut. Ada beberapa tumbuhan di sekitar perisai, semuanya khas negara tersebut: hibiscus merah, tebu dan yucca. Di samping perisai, ada dua...

 

2022 Massachusetts Treasurer and Receiver-General election

2022 Massachusetts Treasurer and Receiver-General election ← 2018 November 8, 2022 2026 →   Nominee Deb Goldberg Cristina Crawford Party Democratic Libertarian Popular vote 1,709,555 516,019 Percentage 76.5% 23.1% County results Municipality resultsGoldberg:      40–50%      50–60%      60–70%      70–80%      80–90%  ...

Zoroastre

Pour les articles homonymes, voir Zoroastre (homonymie). ZoroastreZoroastre par Raphaël, 1509.BiographieNaissance Entre 1500 av. J.-C. et 550 av. J.-C.Lieu inconnuDécès Entre 1500 av. J.-C. et 520 av. J.-C.Lieu inconnuSurnoms Bactrian Sage, le Sage de Bactriane, El sabio bactrianoNationalité PersaneActivités Prophète, écrivain, poète, fondateur d'une religion, thaumaturgePère Pourushaspa Spitāma (d)Mère Dughdova (d)Conjoint Hvōvi (d)Enfants Pourucistā (d)Isat Vastar (d)modifier ...

 

Canale 5

Canale 5CaractéristiquesCréation 24 septembre 1974Propriétaire MediasetSlogan Sempre con teFormat d'image 576i (SDTV) jusque fin 2022, 1080i (HDTV)Langue ItalienPays ItalieStatut Généraliste nationale privéeSiège social RomeAncien nom Telemilanocavo (1974-1978)TeleMilano58 (1978-1980)Site web www.canale5.mediaset.itDiffusionAnalogique  NonNumérique  OuiSatellite  OuiCâble  OuiIPTV  OuiAire Italie Suissemodifier - modifier le code - modifier Wikidata Canale 5 ...

 

Korean Film Archive

Film archive in South Korea This article is about the film archive. For other uses, see Kofa (disambiguation). Korean Film ArchiveHeadquarters (2019)TypeGovernmental, nonprofitPurposePreservation of Korean cinemaHeadquarters400 WorldCupbuk-ro, Mapo District, Seoul, South KoreaParent organizationMinistry of Culture, Sports and TourismWebsiteeng.koreafilm.or.kr/main (in English)Korean nameHangul한국영상자료원Hanja韓國映像資料院Revised RomanizationHanguk yeongsang jaryowonMcCune–...

Bill Withers

Pour les articles homonymes, voir Withers. Si ce bandeau n'est plus pertinent, retirez-le. Cliquez ici pour en savoir plus. Cet article ne cite pas suffisamment ses sources (mars 2021). Si vous disposez d'ouvrages ou d'articles de référence ou si vous connaissez des sites web de qualité traitant du thème abordé ici, merci de compléter l'article en donnant les références utiles à sa vérifiabilité et en les liant à la section « Notes et références ». En pratique ...

 

Ahmad Nami

Ahmad NamiAhmad Nami nel 1925 mentre indossa un abito massonico Primo ministro della SiriaDurata mandato1926 –1928 PredecessoreSubhi Bey Barakat al-Khalidi SuccessoreTaj al-Din al-Hasani LegislaturaXXIX Presidente della SiriaDurata mandato1926 –1928 Al-Damad Ahmad Nami, noto anche con lo pseudonimo di Damat Ahmet Nami (Beirut, 1873 – Beirut, 13 dicembre 1962), è stato un politico siriano, quinto primo ministro della Siria e secondo presidente della Siria dal...

 

SeatGeek Stadium

Stadium This article is about the soccer stadium near Chicago, Illinois, formerly known as Toyota Park. For the two soccer stadiums in Texas see Toyota Stadium and Toyota Field. For other uses, see Toyota Park (disambiguation). SeatGeek StadiumSeatGeek Stadium (then Toyota Park) in 2013SeatGeek StadiumLocation in the Chicago areaShow map of Chicago metropolitan areaSeatGeek StadiumLocation in IllinoisShow map of IllinoisSeatGeek StadiumLocation in the United StatesShow map of the United State...

Grand Prix F1 Abu Dhabi 2014

Grand Prix Abu Dhabi 2014 Lomba ke-19 dari 19 dalam Formula Satu musim 2014← Lomba sebelumnyaLomba berikutnya → Tata Letak Sirkuit Yas Marina.Detail perlombaan[1]Tanggal 23 November 2014Nama resmi 2014 Formula 1 Etihad Airways Abu Dhabi Grand PrixLokasi Sirkuit Yas MarinaPulau Yas, Abu Dhabi,Uni Emirat ArabSirkuit Fasilitas balapan permanenPanjang sirkuit 5.554 km (3.451 mi)Jarak tempuh 55 putaran, 305.355 km (189.739 mi)Cuaca Langit cerah; Suhu udara: 30 ...

 

Copa Campeonato

For the international club competition, see Copa Campeonato del Río de la Plata. Football tournamentCopa CampeonatoThe trophy awarded to championsOrganising bodyAFAFounded2013Abolished2014; 10 years ago (2014)RegionArgentinaNumber of teams2Related competitionsPrimera DivisiónLast championsRiver Plate (2014)Television broadcastersTV PúblicaCanal 26 (UHF and Pay TV) The Copa Campeonato Primera División (familiarly known as Superfinal) was an official Argentine football cup...

 

Cultural rights

Movement asserting the right to practise traditions of culture and language Not to be confused with Cultural right. See also: Economic, social and cultural rights Rights Theoretical distinctions Claim rights and liberty rights Individual and group rights Natural rights and legal rights Negative and positive rights Human rights Civil and political Economic, social and cultural Three generations Rights by beneficiary Accused Animals Children Consumers Creditors Deaf Disabled Elders Farmers Fetu...

Run-of-the-river hydroelectricity

Hydroelectric power station Chief Joseph Dam near Bridgeport, Washington, USA, is a major run-of-the-river station without a sizeable reservoir. A small and floating run-of-the-river power plant in Austria. Run-of-river hydroelectricity (ROR) or run-of-the-river hydroelectricity is a type of hydroelectric generation plant whereby little or no water storage is provided. Run-of-the-river power plants may have no water storage at all or a limited amount of storage, in which case the storage rese...

 

Subic, Zambales

Peta lokasi Subic Subic adalah munisipalitas yang terletak di provinsi Zambales, Filipina. Menurut sensus tahun 2000, wilayah ini memiliki jumlah penduduk sebesar 77.118 jiwa dan 13.882 rumah tangga. Barangay Subic terbagi menjadi 16 barangay. Aningway Sacatihan Asinan Poblacion Asinan Proper Baraca-Camachile (Pob.) Batiawan Calapacuan Calapandayan (Pob.) Cawag Ilwas (Pob.) Mangan-Vaca Matain Naugsol Pamatawan San Isidro Santo Tomas Wawandue (Pob.) Pranala luar Philippine Standard Geographic ...

 

Edmund of Langley, 1st Duke of York

14th-century English prince and nobleman Edmund of LangleyDuke of YorkEdmund of Langley before King Ferdinand I of Portugal, from Jean de Wavrin's Chronique d'AngleterreBorn5 June 1341Kings Langley, Hertfordshire, EnglandDied1 August 1402 (aged 61)Epworth, Lincolnshire, EnglandBurialKing's Langley Priory(1402–1575)All Saints' Church, Kings Langley(since 1575)Spouse Isabella of Castile ​ ​(m. 1372; died 1392)​ Joan Holland ​(m....

Boulaincourt

Peta infrastruktur dan tata guna lahan di Komune Boulaincourt.  = Kawasan perkotaan  = Lahan subur  = Padang rumput  = Lahan pertanaman campuran  = Hutan  = Vegetasi perdu  = Lahan basah  = Anak sungaiBoulaincourt merupakan sebuah komune di departemen Vosges yang terletak pada sebelah timur laut Prancis. Lihat pula Komune di departemen Vosges Referensi INSEE lbsKomune di departemen Vosges Les Ableuvenettes Ahéville Aingeville Ainvelle Allarmont Ambacou...

 

贾宪

《永乐大典》一页 贾宪（？—？），11世纪前半叶中国北宋数学家。陳鈺佐 生平 据《宋史》记载，贾宪曾师从开封府胙城（今河南延津）历算家楚衍，学习天文、历算。《宋史·方技志》记载，楚衍对《九章算术》、《缉古算经》、《海岛算经》都有精深的研究。 贾宪曾任左班殿值，吉隶太史，擅长数学，著有《黄帝九章算经细草》九卷和《释锁算书》等书。《黄帝九章算...