Caioni studied with the Jesuits in Kolozsvár, and continued his studies in Csíksomlyó. In 1647, he became a friar, and continued his studies in Nagyszombat (Trnava), training in music. He was ordained in 1655. Subsequently, he lived in Csíksomlyó, Gyergyószárhegy (Lăzarea), and Mikháza (now Călugăreni, a village in Eremitucommune, Mureș County). He died in Gyergyószárhegy.
His mentioning of the traditional Călușari dance in his musical notations makes this among the first to have ever recorded the custom.
In 1675, Caioni founded a printing press in Csíksomlyó, printing both his works and textbooks for the local Franciscan school. His Cantionale Catolicum went through four editions—1676, 1719, 1805 and 1806. The press was noted for serving the cultural needs of Roman Catholics in the Székely Land and neighbouring Moldavia. It was later used by Hungarianrevolutionaries of 1848 to print their Hadi Lap newspaper, and other publications.
Music
See Five centuries of German music in Transylvania.