In round 1 of the 2016 NRL season, Saifiti made his NRL debut for the Newcastle Knights against the Gold Coast Titans,[8] playing alongside his brother Daniel, becoming the first twins in Australian rugby league's 108-year history to debut together.[9] On 12 May, he and his brother extended their contracts with the Knights from the end of 2017 until the end of 2018. He made a total of 18 appearances for Newcastle in his debut season as the club finished last on the table.[10][11]
2017
Saifiti played 21 games for the Newcastle club in the 2017 season,[12] before having his contract extended until the end of 2020. Newcastle would finish bottom of the table for a third straight season.[13][14]
2018
Saifiti was limited to only eight games for Newcastle in the 2018 NRL season as the club finished 11th on the table.[15]
2019
Saifiti played 7 games for Newcastle in the 2019 NRL season as the club finished 11th on the table.[16]
2020
Saifiti played 21 games for Newcastle in the 2020 NRL season. He played in Newcastle's first finals game since 2013 which was a 46-20 loss against South Sydney in the elimination final.[17]
2021
He played 23 matches for Newcastle in the 2021 NRL season including the club's elimination finals loss against Parramatta.[18]
2022
Saifiti was selected as a reserve player for New South Wales in the 2022 State of Origin series. He made his Origin debut against Queensland after the withdrawal of Jordan McLean in Game 3 of the series at Suncorp Stadium. Saifiti scored a first half try as New South Wales eventually lost the match 22-12.[19]
Saifiti played 23 games for Newcastle in the 2022 NRL season as the club missed the finals finishing 14th on the table.[20]
2023
In round 2 of the 2023 NRL season, Saifiti was sent off for a dangerous high tackle on Wests Tigers player Jake Simpkin. Newcastle would go on to win the match 14-12.[21] Saifiti was later suspended for five matches over the incident.[22]
On 3 July, Saifiti was a surprise selection for New South Wales ahead of their match in game 3 of the 2023 State of Origin series.[23] In round 27, Saifiti captained Newcastle for the first time and scored the opening try in a 32-12 win over the St. George Illawarra Dragons.[24][25]
Saifiti played a total of 21 games for Newcastle in the 2023 NRL season as the club finished 5th on the table. Saifiti played in both finals games as Newcastle were eliminated in the second week of the finals by the New Zealand Warriors.[26]
2024
Saifiti played 16 games for Newcastle in the 2024 NRL season as the club finished 8th and qualified for the finals.[27]
Controversy
On 2 December 2018, Saifiti was found unconscious and with a broken leg after a fight with Dane Cordner, the brother of NSW captain and Sydney Roosters player Boyd Cordner. Saifiti was later cleared of any wrongdoing but was fined $50,000 by Newcastle over the incident.[28]