On June 16, 2022, Netflix first published a trailer for the series and announced that Lucy Walker and Alison Ellwood would be directing, while Alex Gibney would serve as executive producer. Gibney expressed his pleasure working on the project, adding "It’s so important—a revelation about how some hallucinogens, once vilified, can lead to mindfulness. New science shows that these drugs can save lives and change our minds, helping us to live better lives."[1]
According to director Alison Ellwood, the series tries to omit "psychedelic visual tropes—wild colors, rainbow streaks, morphing images" to make it relatable to people who have not had psychedelic experiences.[2]
On Rotten Tomatoes, the miniseries holds an approval rating of 100% based on 9 reviews, with an average rating of 7.40/10.[3] Stuart Heritage of The Guardian called the miniseries "hugely eloquent and convincing".[4] Natalia Winkelman of The Boston Globe criticized the series for being too one-sided and failing to adequately address adverse effects of psychedelics.[5]San Francisco Chronicle critic Bob Strauss found the series "not comprehensive, but packed with interesting tidbits" and says it provided "multiple worthy views that can be mind-blowing."[6]