Guanoxan

Guanoxan
Clinical data
ATC code
Identifiers
  • 2-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)guanidine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H13N3O2
Molar mass207.233 g·mol−1
3D model (JSmol)
  • c1ccc2c(c1)OCC(O2)CNC(=N)N
  • InChI=1S/C10H13N3O2/c11-10(12)13-5-7-6-14-8-3-1-2-4-9(8)15-7/h1-4,7H,5-6H2,(H4,11,12,13) ☒N
  • Key:HIUVKVDQFXDZHU-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Guanoxan is a sympatholytic drug that was marketed as Envacar by Pfizer in the UK to treat high blood pressure. It was not widely used and was eventually withdrawn from the market due to liver toxicity.[1][2]

References

  1. ^ Broadley KJ (1996). Autonomic Pharmacology. CRC Press. p. 276. ISBN 9780748405565.
  2. ^ Wardell WM, Lasagna L (1975). Regulation and drug development. Washington: American Enterprise Institute for Public Policy Research. p. 65. ISBN 9780844731674.



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